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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T73692 | Parathyroid hormone | ||
Parathyroid hormone (PTH), an 84-amino acid circulating hormone synthesized in the parathyroid glands, primarily regulates bone and kidney functions to maintain extracellular calcium levels within normal ranges. It is al... | |||
T21535 | Parathyroid Hormone (1-34), bovine | Thyroid hormone receptor(THR) | |
Parathyroid Hormone (1-34), bovine is a parathyroid hormone (PTH) receptor agonist that is part of the parathyroid hormone family. Parathyroid Hormone (1-34), bovine is used to study osteoporosis and hypoparathyroidism. | |||
T36767 | Parathyroid Hormone (1-13) (trifluoroacetate salt) | ||
Parathyroid hormone (PTH) (1-13) is an N-terminal fragment of PTH (1-34) . In vivo, PTH (1-13) (0.003-1 μmol/kg) increases mean arterial pressure (MAP) in anesthetized rats. | |||
TP1964 | Parathyroid hormone (1-34) (rat) | ||
Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats. | |||
TP2283 | parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] | Others | |
parathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis] is a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH) is secreted by the chief cells of the parathyroid... | |||
T76084 | Parathyroid Hormone (1-34), human, biotinylated | ||
Parathyroid Hormone (1-34), human, biotinylated serves as a probe targeting the parathyroid hormone receptor. It is utilized in the analysis of interactions between parathyroid hormone and its receptors within living cel... | |||
T76061 | Parathyroid hormone (1-34) (rat) acetate | ||
Parathyroid hormone (1-34) (rat) (acetate) is a parathyroid hormone variant that enhances the structure of both cortical and cancellous bones. It is utilized in osteoporosis research [1] [2]. | |||
T75867 | Parathyroid Hormone (1-34), bovine TFA | ||
Parathyroid Hormone (1-34), bovine TFA, a potent agonist of the parathyroid hormone (PTH) receptor, elevates calcium and inorganic phosphate levels in vivo. This compound is employed in osteoporosis research [1]. | |||
T21460 | Teriparatide acetate | hPTH 1-34 (acetate salt),Parathar acetate,Forteo | Others |
Teriparatide acetate (Forteo) is a PHT agonist, with an IC50 of 2 nM in HEK293 cells.Teriparatide acetate is a recombinant form of parathyroid hormone. It is an effective anabolic (i.e., bone growing) agent used to treat... | |||
T13128 | Teriparatide | Human parathyroid hormone-(1-34),hPTH (1-34),PTH 1-34 | Others |
Teriparatide is an agonist of PHT(IC50 of 2 nM in HEK293 cells). | |||
T2406 | Cinacalcet hydrochloride | AMG-073 HCl,Cinacalcet HCl,AMG-073 hydrochloride,Cinacalcet | CaSR |
Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces para... | |||
T16015 | Maxacalcitol | 22-Oxacalcitriol | Others |
Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue. Maxacalcitol inhibits parathyroid hormone (PTH) mRNA expression in vitro and in vivo. | |||
TP1215L | Abaloparatide acetate(247062-33-5 free base) | Others | |
Abaloparatide acetate is a parathyroid hormone receptor 1 PTHR1 analogue and an effective and selective activator of the PTHR1 signaling pathway. | |||
TP1215 | Abaloparatide TFA | BA 058 TFA,Abaloparatide TFA (247062-33-5 free base),BIM 44058 TFA | Others |
Abaloparatide TFA (BIM 44058 TFA) is a parathyroid hormone-related protein (PTHrP) analog drug used to treat osteoporosis like the related drug teriparatide. | |||
T9691L | (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate | Thyroid hormone receptor(THR) | |
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membrane. | |||
T29067 | Upacicalcet | PLS-240,SK-1403,AJT-240 | Calcium Channel |
Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-s... | |||
TP1236 | Etelcalcetide hydrochloride | AMG 416 hydrochloride,KAI-4169 hydrochloride | CaSR |
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that acts as an allosteric modulator of the calcium-sensing receptor (CaSR), effectively lowering parathyroid hormone (PTH) levels in patients wi... | |||
T6316 | Calcitriol | Topitriol,Rocaltrol,Calcijex,RO215535,1,25-Dihydroxyvitamin D3 | Endogenous Metabolite |
Calcitriol (1,25-Dihydroxyvitamin D3) is a metabolite of vitamin D and a vitamin D receptor (VDR) agonist (IC50=0.4 nM). Calcitriol increases intestinal absorption of calcium and phosphorus, and increases bone resorption... | |||
T16442 | PCO371 | 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl- | Thyroid hormone receptor(THR) |
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon... | |||
T29067L | Upacicalcet HCl | Upacicalcet HCl(1333218-50-0 Free base) | CaSR |
Upacicalcet HCl is an intravesical calcium mimetic that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on calcium-sensitive receptors in parathyroid cell membranes, thereby lowering PTH levels ... |